{"id":3118,"date":"2025-10-06T18:41:00","date_gmt":"2025-10-06T10:41:00","guid":{"rendered":"https:\/\/www.huanqiukexue.com\/?p=3118"},"modified":"2025-10-11T16:00:11","modified_gmt":"2025-10-11T08:00:11","slug":"%e8%af%a6%e8%a7%a32025%e8%af%ba%e8%b4%9d%e5%b0%94%e7%94%9f%e7%90%86%e5%ad%a6%e6%88%96%e5%8c%bb%e5%ad%a6%e5%a5%96%ef%bc%9a%e4%bb%96%e4%bb%ac%e5%8f%91%e7%8e%b0%e4%ba%86%e4%ba%ba%e4%bd%93%e8%87%aa","status":"publish","type":"post","link":"https:\/\/www.huanqiukexue.com\/?p=3118","title":{"rendered":"\u8be6\u89e32025\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\uff1a\u4ed6\u4eec\u53d1\u73b0\u4e86\u4eba\u4f53\u81ea\u6211\u4fdd\u62a4\u7684\u201c\u5b89\u5168\u536b\u58eb\u201d\uff0c\u4e3a\u764c\u75c7\u3001\u81ea\u8eab\u514d\u75ab\u75c5\u7684\u65b0\u7597\u6cd5\u5960\u5b9a\u57fa\u7840"},"content":{"rendered":"\n<p><strong>2025 \u5e74 10 \u6708 6 \u65e5\u5317\u4eac\u65f6\u95f4 17 \u65f6 30 \u5206\u8bb8\uff0c2 \u4f4d\u7f8e\u56fd\u79d1\u5b66\u5bb6\u739b\u4e3d\u00b7E\u00b7\u5e03\u4f26\u79d1\uff08Mary E. Brunkow\uff09\u3001\u5f17\u96f7\u5fb7\u00b7\u62c9\u59c6\u65af\u5fb7\u5c14\uff08Fred Ramsdell\uff09\u548c 1 \u4f4d\u65e5\u672c\u79d1\u5b66\u5bb6\u5742\u53e3\u5fd7\u6587\uff08Shimon Sakaguchi\uff09\u56e0\u5728\u5916\u5468\u514d\u75ab\u8010\u53d7\u65b9\u9762\u7684\u53d1\u73b0\uff0c\u83b7\u5f97 2025 \u5e74\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u3002<\/strong><\/p>\n\n\n\n<p>\u739b\u4e3d\u00b7E\u00b7\u5e03\u4f26\u79d1\uff08Mary E. Brunkow\uff09\uff0c1961 \u5e74\u51fa\u751f\u3002\u535a\u58eb\u6bd5\u4e1a\u4e8e\u7f8e\u56fd\u666e\u6797\u65af\u987f\u5927\u5b66\u3002\u73b0\u4efb\u7f8e\u56fd\u897f\u96c5\u56fe\u7cfb\u7edf\u751f\u7269\u5b66\u7814\u7a76\u6240\uff08Institute for Systems Biology, ISB\uff09\u9ad8\u7ea7\u9879\u76ee\u7ecf\u7406\u3002ISB \u5b98\u7f51\u663e\u793a\uff0c\u5979\u4e00\u76f4\u81f4\u529b\u4e8e\u652f\u6301\u5404\u79cd\u75be\u75c5\u9886\u57df\u7684\u5bb6\u65cf\u57fa\u56e0\u7ec4\u5b66\u3001\u83b1\u59c6\u75c5\u7684\u7cfb\u7edf\u751f\u7269\u5b66\u3001\u8d25\u8840\u75c7\u751f\u7269\u6807\u5fd7\u7269\u548c\u79d1\u5b66\u5065\u5eb7\u7b49\u591a\u4e2a\u9886\u57df\u7684\u4e0d\u540c\u9879\u76ee\u3002<\/p>\n\n\n\n<p>\u5f17\u96f7\u5fb7\u00b7\u62c9\u59c6\u65af\u5fb7\u5c14\uff08Fred Ramsdell\uff09\uff0c1960\u5e74\u51fa\u751f\u30021987\u5e74\u4e8e\u7f8e\u56fd\u52a0\u5dde\u5927\u5b66\u6d1b\u6749\u77f6\u5206\u6821\u83b7\u5f97\u514d\u75ab\u5b66\u535a\u58eb\u5b66\u4f4d\uff0c\u968f\u540e\u5728\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662\u4ece\u4e8b\u535a\u58eb\u540e\u7814\u7a76\u3002\u62c9\u59c6\u65af\u5fb7\u5c14\u66fe\u5728 Darwin Molecular\/Celltech\u3001ZymoGenetics\u3001Novo Nordisk \u548c aTyr Pharma \u7b49\u591a\u5bb6\u751f\u7269\u6280\u672f\u516c\u53f8\u62c5\u4efb\u9ad8\u7ea7\u7ba1\u7406\u4eba\u5458\uff0c\u73b0\u4efb\u7f8e\u56fd\u65e7\u91d1\u5c71\u7d22\u8bfa\u739b\u751f\u7269\u6cbb\u7597\u516c\u53f8\uff08Sonoma Biotherapeutics\uff09\u79d1\u5b66\u987e\u95ee\u3002\u62c9\u59c6\u65af\u5fb7\u5c14\u548c\u56e2\u961f\u5728\u591a\u9cde\u5c51\u5c0f\u9f20\uff08scurfy mice\uff09\u548c\u60a3\u6709 IPEX \u7efc\u5408\u5f81\uff08\u4e00\u79cd\u4e25\u91cd\u7684\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff09\u7684\u513f\u7ae5\u4e2d\u9274\u5b9a\u51fa\u81f4\u75c5\u57fa\u56e0&nbsp;<em>FOXP3<\/em>\uff0c\u5e76\u8fdb\u4e00\u6b65\u786e\u5b9a&nbsp;<em>FOXP3<\/em>&nbsp;\u5728\u8c03\u8282\u6027 T \u7ec6\u80de\u7684\u53d1\u80b2\u4e2d\u8d77\u7740\u81f3\u5173\u91cd\u8981\u7684\u4f5c\u7528\u30022017 \u5e74\uff0c\u62c9\u59c6\u65af\u5fb7\u5c14\u4e0e\u5742\u53e3\u5fd7\u6587\u3001 Alexander Rudensky \u5171\u540c\u83b7\u5f97\u4e86\u591a\u53d1\u6027\u5173\u8282\u708e\u7814\u7a76\u7684\u514b\u62c9\u798f\u5fb7\u5956\u3002\u4ed6\u56e0\u201c\u53d1\u73b0\u8c03\u8282\u6027 T \u7ec6\u80de\u4e2d\u548c\u5173\u8282\u708e\u548c\u5176\u4ed6\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u4e2d\u7684\u7834\u574f\u6027\u514d\u75ab\u53cd\u5e94\u201d\u800c\u95fb\u540d\u3002<\/p>\n\n\n\n<p>\u5742\u53e3\u5fd7\u6587\uff08Shimon Sakaguchi\uff09\uff0c1951 \u5e74\u51fa\u751f\u3002\u5148\u540e\u4e8e 1976 \u5e74\u548c 1983 \u5e74\u83b7\u5f97\u65e5\u672c\u4eac\u90fd\u5927\u5b66\u533b\u5b66\u535a\u58eb\u5b66\u4f4d\u548c\u54f2\u5b66\u535a\u58eb\u5b66\u4f4d\uff0c\u968f\u540e\u524d\u5f80\u7f8e\u56fd\u7ea6\u7ff0\u00b7\u970d\u666e\u91d1\u65af\u5927\u5b66\u548c\u65af\u5766\u798f\u5927\u5b66\u62c5\u4efb\u5ba2\u5ea7\u7814\u7a76\u5458\uff0c1999 \u5e74\u62c5\u4efb\u4eac\u90fd\u5927\u5b66\u6559\u6388\uff0c2007 \u5e74\u62c5\u4efb\u4eac\u90fd\u5927\u5b66\u518d\u751f\u533b\u79d1\u5b66\u7814\u7a76\u6240\u6240\u957f\u3002\u73b0\u4efb\u65e5\u672c\u5927\u962a\u5927\u5b66\u514d\u75ab\u5b66\u524d\u6cbf\u7814\u7a76\u4e2d\u5fc3\u7279\u8058\u6559\u6388\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_12.jpg\" alt=\"\" class=\"wp-image-3124\" srcset=\"https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_12.jpg 600w, https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_12-300x300.jpg 300w, https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_12-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"47\" src=\"https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_6-3.jpg\" alt=\"\" class=\"wp-image-3120\" srcset=\"https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_6-3.jpg 600w, https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_6-3-300x24.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure>\n\n\n\n<p><br>\u4eba\u4f53\u5f3a\u5927\u7684\u514d\u75ab\u7cfb\u7edf\u5fc5\u987b\u53d7\u5230\u8c03\u63a7\uff0c\u5426\u5219\u5b83\u53ef\u80fd\u4f1a\u653b\u51fb\u6211\u4eec\u81ea\u8eab\u7684\u5668\u5b98\u3002\u739b\u4e3d\u00b7E\u00b7\u5e03\u4f26\u79d1\uff08Mary E. Brunkow\uff09\u3001\u5f17\u96f7\u5fb7\u00b7\u62c9\u59c6\u65af\u5fb7\u5c14\uff08Fred Ramsdell\uff09\u548c\u5742\u53e3\u5fd7\u6587\uff08Shimon Sakaguchi\uff09\u56e0\u5728\u5916\u5468\u514d\u75ab\u8010\u53d7\u65b9\u9762\u7684\u7a81\u7834\u6027\u53d1\u73b0\uff0c\u88ab\u6388\u4e882025\u5e74\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u3002\u8fd9\u4e9b\u53d1\u73b0\u63ed\u793a\u4e86\u514d\u75ab\u7cfb\u7edf\u5982\u4f55\u907f\u514d\u4f24\u5bb3\u4eba\u4f53\u3002\u4ed6\u4eec\u7684\u53d1\u73b0\u4e3a\u4e00\u4e2a\u65b0\u7684\u7814\u7a76\u9886\u57df\u5960\u5b9a\u4e86\u57fa\u7840\uff0c\u5e76\u63a8\u52a8\u4e86\u65b0\u7597\u6cd5\u7684\u7814\u53d1\uff0c\u4f8b\u5982\u9488\u5bf9\u764c\u75c7\u548c\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u7597\u6cd5\u3002<\/p>\n\n\n\n<p><br>\u514d\u75ab\u7cfb\u7edf\u662f\u6f14\u5316\u53f2\u4e0a\u7684\u6770\u4f5c\u3002\u5b83\u6bcf\u5929\u4fdd\u62a4\u6211\u4eec\u514d\u53d7\u6210\u5343\u4e0a\u4e07\u79cd\u8bd5\u56fe\u5165\u4fb5\u4eba\u4f53\u7684\u75c5\u6bd2\u3001\u7ec6\u83cc\u548c\u5176\u4ed6\u5fae\u751f\u7269\u7684\u4fb5\u5bb3\u3002\u5982\u679c\u6ca1\u6709\u4e00\u4e2a\u529f\u80fd\u6b63\u5e38\u7684\u514d\u75ab\u7cfb\u7edf\uff0c\u6211\u4eec\u5c06\u65e0\u6cd5\u751f\u5b58\u3002<\/p>\n\n\n\n<p><br>\u514d\u75ab\u7cfb\u7edf\u7684\u4e00\u5927\u5947\u8ff9\u662f\u5b83\u80fd\u591f\u8bc6\u522b\u75c5\u539f\u4f53\uff0c\u5e76\u5c06\u5176\u4e0e\u4eba\u4f53\u81ea\u8eab\u7684\u7ec6\u80de\u533a\u5206\u5f00\u6765\u3002\u5a01\u80c1\u6211\u4eec\u5065\u5eb7\u7684\u5fae\u751f\u7269\u5e76\u975e\u7a7f\u7740\u7edf\u4e00\u7684\u201c\u5236\u670d\u201d\u2014\u2014\u5b83\u4eec\u5404\u6709\u4e0d\u540c\u7684\u5916\u89c2\u3002\u8bb8\u591a\u5fae\u751f\u7269\u8fd8\u6f14\u5316\u51fa\u4e86\u4e0e\u4eba\u4f53\u7ec6\u80de\u76f8\u4f3c\u7684\u7279\u5f81\uff0c\u4ee5\u4f5c\u4e3a\u4f2a\u88c5\u3002\u90a3\u4e48\uff0c\u514d\u75ab\u7cfb\u7edf\u5982\u4f55\u5206\u8fa8\u5e94\u8be5\u653b\u51fb\u4ec0\u4e48\u548c\u4fdd\u62a4\u4ec0\u4e48\u5462\uff1f\u4e3a\u4ec0\u4e48\u514d\u75ab\u7cfb\u7edf\u4e0d\u4f1a\u9891\u7e41\u653b\u51fb\u6211\u4eec\u81ea\u8eab\u7684\u8eab\u4f53\u5462\uff1f<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"400\" src=\"https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_3-3.jpg\" alt=\"\" class=\"wp-image-3127\" srcset=\"https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_3-3.jpg 600w, https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_3-3-300x200.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure>\n\n\n\n<p><span style=\"color: rgb(153, 153, 153); font-size: 16px; letter-spacing: 1px;\">\u00a9 \u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u59d4\u5458\u4f1a\u3002\u56fe\uff1aMattias Karl\u00e9n<br><\/span><\/p>\n\n\n\n<p>\u957f\u671f\u4ee5\u6765\uff0c\u7814\u7a76\u4eba\u5458\u8ba4\u4e3a\u4ed6\u4eec\u5df2\u7ecf\u4e86\u89e3\u4e86\u8fd9\u4e9b\u95ee\u9898\u7684\u7b54\u6848\uff1a\u514d\u75ab\u7ec6\u80de\u901a\u8fc7\u4e00\u4e2a\u79f0\u4e3a\u4e2d\u67a2\u514d\u75ab\u8010\u53d7\uff08central immune tolerance\uff09\u7684\u8fc7\u7a0b\u6210\u719f\u3002\u7136\u800c\uff0c\u4e8b\u5b9e\u8bc1\u660e\uff0c\u6211\u4eec\u7684\u514d\u75ab\u7cfb\u7edf\u6bd4\u4ed6\u4eec\u60f3\u8c61\u7684\u8981\u590d\u6742\u5f97\u591a\u3002\u739b\u4e3d\u00b7\u5e03\u4f26\u79d1\u3001\u5f17\u96f7\u5fb7\u00b7\u62c9\u59c6\u65af\u5fb7\u5c14\u548c\u5742\u53e3\u5fd7\u6587\u56e0\u5728\u5916\u5468\u514d\u75ab\u8010\u53d7\uff08peripheral immune toleranc\uff09\u65b9\u9762\u7684\u53d1\u73b0\u800c\u88ab\u6388\u4e882025\u5e74\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u3002\u4eca\u5e74\u7684\u8bfa\u8d1d\u5c14\u5956\u5f97\u4e3b\u4eec\u8bc6\u522b\u51fa\u4e86\u514d\u75ab\u7cfb\u7edf\u7684\u201c\u5b89\u5168\u536b\u58eb\u201d\u2014\u2014\u8c03\u8282\u6027T\u7ec6\u80de\uff08regulatory T cells\uff09\uff0c\u4ece\u800c\u4e3a\u4e00\u4e2a\u65b0\u7684\u7814\u7a76\u9886\u57df\u5960\u5b9a\u4e86\u57fa\u7840\u3002\u8fd9\u4e9b\u53d1\u73b0\u8fd8\u4fc3\u6210\u4e86\u6f5c\u5728\u533b\u7597\u65b9\u6cd5\u7684\u53d1\u5c55\uff0c\u8fd9\u4e9b\u65b9\u6cd5\u76ee\u524d\u6b63\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u8fdb\u884c\u8bc4\u4f30\u3002\u4eba\u4eec\u5e0c\u671b\u80fd\u591f\u6cbb\u7597\u6216\u6cbb\u6108\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff0c\u5f00\u53d1\u66f4\u6709\u6548\u7684\u764c\u75c7\u7597\u6cd5\uff0c\u5e76\u9884\u9632\u5e72\u7ec6\u80de\u79fb\u690d\u540e\u7684\u4e25\u91cd\u5e76\u53d1\u75c7\u3002<\/p>\n\n\n\n<p><br>\u8ba9\u6211\u4eec\u4e3a\u4eca\u5e74\u7684\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u62c9\u5f00\u5e8f\u5e55\uff0c\u9996\u5148\u7b80\u8981\u4ecb\u7ecd\u4e00\u4e0b20\u4e16\u7eaa90\u5e74\u4ee3\u7814\u7a76\u4eba\u5458\u5bf9\u514d\u75ab\u7cfb\u7edfT\u7ec6\u80de\u7684\u4e86\u89e3\u3002\u8fd9\u4e9b\u5bf9\u4e8e\u4eba\u4f53\u6765\u8bf4\u81f3\u5173\u91cd\u8981\u7684\u4fdd\u62a4\u8005\uff0c\u662f\u6211\u4eec\u6545\u4e8b\u7684\u6838\u5fc3\u3002<\/p>\n\n\n<p class=\"has-text-align-center has-medium-font-size\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0);\"><span style=\"font-size: 24px; text-decoration: overline; caret-color: rgb(8,124,186); color: rgb(8,124,186);\"><br><br><strong>T\u7ec6\u80de\u2014\u2014\u8eab\u4f53\u9632\u5fa1\u7684\u5173\u952e\u89d2\u8272\n<\/strong><\/span><\/mark><\/strong><\/p>\n\n\n<p>\u8f85\u52a9\u6027T\u7ec6\u80de\u4f1a\u5728\u4f53\u5185\u4e0d\u65ad\u5de1\u903b\u3002\u5982\u679c\u5b83\u4eec\u53d1\u73b0\u5165\u4fb5\u7684\u5fae\u751f\u7269\uff0c\u5c31\u4f1a\u5411\u5176\u4ed6\u514d\u75ab\u7ec6\u80de\u53d1\u51fa\u8b66\u62a5\uff0c\u540e\u8005\u968f\u5373\u53d1\u8d77\u653b\u51fb\u3002<\/p>\n\n\n\n<p><br>\u6740\u4f24\u6027T\u7ec6\u80de\u4f1a\u6e05\u9664\u88ab\u75c5\u6bd2\u6216\u5176\u4ed6\u75c5\u539f\u4f53\u611f\u67d3\u7684\u7ec6\u80de\u3002\u5b83\u4eec\u4e5f\u53ef\u4ee5\u653b\u51fb\u80bf\u7624\u7ec6\u80de\u3002<\/p>\n\n\n\n<p><br>\u9664\u6b64\u4e4b\u5916\uff0c\u8fd8\u6709\u5176\u4ed6\u5177\u6709\u4e0d\u540c\u529f\u80fd\u7684\u514d\u75ab\u7ec6\u80de\u3002\u7136\u800c\uff0c\u6211\u4eec\u4e0d\u4f1a\u5173\u6ce8\u8fd9\u4e9b\u7ec6\u80de\uff0c\u56e0\u4e3a\u5728\u8fd9\u4e2a\u6545\u4e8b\u4e2d\uff0cT\u7ec6\u80de\u662f\u4e3b\u89d2\u3002<\/p>\n\n\n<p class=\"has-text-align-center has-medium-font-size\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0);\"><span style=\"font-size: 24px; text-decoration: overline; caret-color: rgb(8,124,186); color: rgb(8,124,186);\"><br><br><strong>\u80fd\u591f\u53d1\u73b0\u5165\u4fb5\u8005\u7684\u4f20\u611f\u5668\n<\/strong><\/span><\/mark><\/strong><\/p><p><br>\u6240\u6709T\u7ec6\u80de\u8868\u9762\u90fd\u6709\u4e00\u79cd\u53eb\u505aT\u7ec6\u80de\u53d7\u4f53\uff08T-cell receptors\uff09\u7684\u7279\u6b8a\u86cb\u767d\u8d28\u3002\u8fd9\u4e9b\u53d7\u4f53\u53ef\u4ee5\u6bd4\u4f5c\u4e00\u79cd\u4f20\u611f\u5668\u3002\u901a\u8fc7\u5b83\u4eec\uff0cT\u7ec6\u80de\u53ef\u4ee5\u626b\u63cf\u5176\u4ed6\u7ec6\u80de\uff0c\u4ee5\u53d1\u73b0\u8eab\u4f53\u662f\u5426\u53d7\u5230\u653b\u51fb\u3002T\u7ec6\u80de\u53d7\u4f53\u7684\u7279\u6b8a\u4e4b\u5904\u5728\u4e8e\uff0c\u5b83\u4eec\u50cf\u62fc\u56fe\u4e00\u6837\uff0c\u5f62\u72b6\u5404\u4e0d\u76f8\u540c\u3002\u5b83\u4eec\u7531\u8bb8\u591a\u968f\u673a\u7ec4\u5408\u7684\u57fa\u56e0\u6784\u5efa\u800c\u6210\u3002\u7406\u8bba\u4e0a\uff0c\u8fd9\u610f\u5473\u7740\u8eab\u4f53\u53ef\u4ee5\u5236\u9020\u8d85\u8fc710\u00b9\u2075\u79cd\u4e0d\u540c\u7684T\u7ec6\u80de\u53d7\u4f53\u3002<\/p>\n\n\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"333\" src=\"https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_5-4.jpg\" alt=\"\" class=\"wp-image-3126\" srcset=\"https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_5-4.jpg 600w, https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_5-4-300x167.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure>\n\n\n\n<p><span style=\"color: rgb(153, 153, 153); font-size: 16px; letter-spacing: 1px;\">\u56fe2. T\u7ec6\u80de\u5982\u4f55\u53d1\u73b0\u75c5\u6bd2 \u00a9 \u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u59d4\u5458\u4f1a\u3002\u56fe\uff1aMattias Karl\u00e9n<\/span><\/p>\n\n\n\n<p><br>\u6570\u91cf\u5e9e\u5927\u3001\u53d7\u4f53\u5404\u5f02\u7684T\u7ec6\u80de\u786e\u4fdd\u4e86\u603b\u6709\u4e00\u4e9b\u7ec6\u80de\u80fd\u591f\u68c0\u6d4b\u5230\u5165\u4fb5\u5fae\u751f\u7269\u7684\u5f62\u72b6\uff08\u56fe2\uff09\uff0c\u5305\u62ec\u50cf2019\u5e74\u5f15\u53d1COVID-19\u5927\u6d41\u884c\u7684\u65b0\u578b\u75c5\u6bd2\u3002\u7136\u800c\uff0c\u8eab\u4f53\u4e5f\u4e0d\u53ef\u907f\u514d\u5730\u4f1a\u4ea7\u751f\u80fd\u591f\u7ed3\u5408\u81ea\u8eab\u7ec4\u7ec7\u7684T\u7ec6\u80de\u53d7\u4f53\u3002\u90a3\u4e48\uff0c\u662f\u4ec0\u4e48\u8ba9T\u7ec6\u80de\u5bf9\u654c\u5bf9\u5fae\u751f\u7269\u4ea7\u751f\u53cd\u5e94\uff0c\u800c\u5bf9\u6211\u4eec\u81ea\u8eab\u7684\u7ec6\u80de\u5374\u4e0d\u4ea7\u751f\u53cd\u5e94\u5462\uff1f<\/p>\n\n\n<p class=\"has-text-align-center has-medium-font-size\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0);\"><span style=\"font-size: 24px; text-decoration: overline; caret-color: rgb(8,124,186); color: rgb(8,124,186);\"><br><br><strong>\u8bc6\u522b\u81ea\u8eab\u7ec4\u7ec7\u7684T\u7ec6\u80de\u88ab\u6e05\u9664<\/strong><\/span><\/mark><\/strong><\/p><p>\u572820\u4e16\u7eaa80\u5e74\u4ee3\uff0c\u7814\u7a76\u4eba\u5458\u4e86\u89e3\u5230\uff0c\u5f53T\u7ec6\u80de\u5728\u80f8\u817a\u4e2d\u6210\u719f\u65f6\uff0c\u5b83\u4eec\u4f1a\u7ecf\u5386\u4e00\u79cd\u6d4b\u8bd5\uff0c\u90a3\u4e9b\u8bc6\u522b\u8eab\u4f53\u81ea\u8eab\uff0c\u5373\u5185\u6e90\u6027\u86cb\u767d\u8d28\u7684T\u7ec6\u80de\u4f1a\u88ab\u6e05\u9664\uff08\u56fe3\uff09\u3002\u8fd9\u4e2a\u7b5b\u9009\u8fc7\u7a0b\u88ab\u79f0\u4e3a\u4e2d\u67a2\u8010\u53d7\uff08central tolerance\uff09\u3002<\/p>\n\n\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"333\" src=\"https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_4-3.jpg\" alt=\"\" class=\"wp-image-3125\" srcset=\"https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_4-3.jpg 600w, https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_4-3-300x167.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure>\n\n\n\n<p><span style=\"color: rgb(153, 153, 153); font-size: 16px; letter-spacing: 1px;\">\u56fe3. \u6709\u5bb3T\u7ec6\u80de\u5982\u4f55\u88ab\u6e05\u9664 \u00a9 \u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u59d4\u5458\u4f1a\u3002\u56fe\uff1aMattias Karl\u00e9n<\/span><\/p>\n\n\n\n<p><br>\u9664\u6b64\u4e4b\u5916\uff0c\u4e00\u4e9b\u7814\u7a76\u4eba\u5458\u6000\u7591\u5b58\u5728\u4e00\u79cd\u7ec6\u80de\uff0c\u4ed6\u4eec\u79f0\u4e4b\u4e3a\u6291\u5236\u6027T\u7ec6\u80de\uff08suppressor T cells\uff09\u3002\u4ed6\u4eec\u8ba4\u4e3a\u8fd9\u4e9b\u7ec6\u80de\u8d1f\u8d23\u5904\u7406\u90a3\u4e9b\u901a\u8fc7\u4e86\u80f8\u817a\u6d4b\u8bd5\u7684\u201c\u6f0f\u7f51\u4e4b\u9c7c\u201dT\u7ec6\u80de\u3002\u7136\u800c\uff0c\u8be5\u9886\u57df\u7684\u4e00\u4e9b\u7814\u7a76\u4eba\u5458\u4ece\u4ed6\u4eec\u5b9e\u9a8c\u4e2d\u5f97\u51fa\u7684\u7ed3\u8bba\u5f88\u7275\u5f3a\u3002\u5f53\u4e00\u4e9b\u652f\u6301\u6291\u5236\u6027T\u7ec6\u80de\u5b58\u5728\u7684\u8bc1\u636e\u88ab\u8bc1\u660e\u9519\u8bef\u540e\uff0c\u7814\u7a76\u4eba\u5458\u5426\u5b9a\u4e86\u6574\u4e2a\u5047\u8bf4\uff0c\u8be5\u7814\u7a76\u9886\u57df\u4e5f\u6216\u591a\u6216\u5c11\u5730\u88ab\u653e\u5f03\u4e86\u3002<\/p>\n\n\n\n<p><br>\u7136\u800c\uff0c\u6709\u4e00\u4f4d\u7814\u7a76\u4eba\u5458\u9006\u6d41\u800c\u4e0a\u3002\u4ed6\u7684\u540d\u5b57\u662f\u5742\u53e3\u5fd7\u6587\uff0c\u4ed6\u5f53\u65f6\u5728\u65e5\u672c\u540d\u53e4\u5c4b\u7684\u7231\u77e5\u53bf\u764c\u75c7\u4e2d\u5fc3\u7814\u7a76\u6240\uff08Aichi Cancer Center Research Institute\uff09\u5de5\u4f5c\u3002<\/p>\n\n\n<p class=\"has-text-align-center has-medium-font-size\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0);\"><span style=\"font-size: 24px; text-decoration: overline; caret-color: rgb(8,124,186); color: rgb(8,124,186);\"><br><br><strong>\u5742\u53e3\u5fd7\u6587\u7684\u6d1e\u89c1\uff1a\u514d\u75ab\u7cfb\u7edf\u5fc5\u5b9a\u6709\u4e00\u4f4d\u201c\u5b89\u5168\u536b\u58eb\u201d<\/strong><\/span><\/mark><\/strong><\/p><p>\u5742\u53e3\u5fd7\u6587\u7684\u7814\u7a76\u7075\u611f\u6765\u81ea\u4e8e\u4ed6\u540c\u4e8b\u65e9\u524d\u8fdb\u884c\u7684\u4e00\u9879\u5b58\u5728\u77db\u76fe\u7684\u5b9e\u9a8c\u3002\u4e3a\u4e86\u4e86\u89e3\u80f8\u817a\u5728T\u7ec6\u80de\u53d1\u80b2\u4e2d\u7684\u4f5c\u7528\uff0c\u4ed6\u4eec\u901a\u8fc7\u624b\u672f\u5207\u9664\u4e86\u65b0\u751f\u5c0f\u9f20\u7684\u80f8\u817a\u3002\u4ed6\u4eec\u5047\u8bbe\u8fd9\u4e9b\u5c0f\u9f20\u4f1a\u4ea7\u751f\u66f4\u5c11\u7684T\u7ec6\u80de\uff0c\u514d\u75ab\u7cfb\u7edf\u4e5f\u4f1a\u66f4\u5f31\u3002\u7136\u800c\uff0c\u5982\u679c\u624b\u672f\u5728\u5c0f\u9f20\u51fa\u751f\u4e09\u5929\u540e\u8fdb\u884c\uff0c\u514d\u75ab\u7cfb\u7edf\u5c31\u4f1a\u8fc7\u5ea6\u6d3b\u8dc3\u5e76\u5931\u63a7\uff0c\u5bfc\u81f4\u5c0f\u9f20\u60a3\u4e0a\u4e00\u7cfb\u5217\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3002<br>\u4e3a\u4e86\u66f4\u597d\u5730\u7406\u89e3\u8fd9\u4e00\u73b0\u8c61\uff0c\u572820\u4e16\u7eaa80\u5e74\u4ee3\u521d\uff0c\u5742\u53e3\u5fd7\u6587\u4ece\u57fa\u56e0\u76f8\u540c\u7684\u5c0f\u9f20\u4f53\u5185\u5206\u79bb\u51fa\u6210\u719f\u7684T\u7ec6\u80de\uff0c\u5e76\u5c06\u5176\u6ce8\u5c04\u5230\u6ca1\u6709\u80f8\u817a\u7684\u5c0f\u9f20\u4f53\u5185\u3002\u8fd9\u4ea7\u751f\u4e86\u4e00\u4e2a\u6709\u8da3\u7684\u6548\u679c\uff1a\u4f3c\u4e4e\u5b58\u5728\u4e00\u79cd\u80fd\u591f\u4fdd\u62a4\u5c0f\u9f20\u514d\u53d7\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u4fb5\u5bb3\u7684T\u7ec6\u80de\uff08\u56fe4\uff09\u3002<\/p>\n\n\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"333\" src=\"https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_9.jpg\" alt=\"\" class=\"wp-image-3122\" srcset=\"https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_9.jpg 600w, https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_9-300x167.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure>\n\n\n\n<p><span style=\"color: rgb(153, 153, 153); font-size: 16px; letter-spacing: 1px;\">\u56fe4. \u542f\u53d1\u5742\u53e3\u5fd7\u6587\u7684\u5b9e\u9a8c \u00a9 \u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u59d4\u5458\u4f1a\u3002\u56fe\uff1aMattias Karl\u00e9n<\/span><\/p>\n\n\n\n<p><br>\u8fd9\u9879\u7814\u7a76\u53d1\u73b0\u4ee5\u53ca\u5176\u4ed6\u7c7b\u4f3c\u7684\u7ed3\u679c\u4f7f\u5742\u53e3\u5fd7\u6587\u786e\u4fe1\uff0c\u514d\u75ab\u7cfb\u7edf\u5fc5\u5b9a\u6709\u67d0\u79cd\u5f62\u5f0f\u7684\u201c\u5b89\u5168\u536b\u58eb\u201d\uff0c\u80fd\u591f\u5e73\u606f\u5176\u4ed6T\u7ec6\u80de\u7684\u6d3b\u52a8\u5e76\u5bf9\u5176\u8fdb\u884c\u6291\u5236\u3002\u4f46\u8fd9\u662f\u54ea\u79cd\u7ec6\u80de\u5462\uff1f<\/p>\n\n\n\n<p class=\"has-text-align-center has-medium-font-size\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0);\"><span style=\"font-size: 24px; text-decoration: overline; caret-color: rgb(8,124,186); color: rgb(8,124,186);\"><br><br><strong>\u5742\u53e3\u5fd7\u6587\u53d1\u73b0\u4e00\u7c7b\u65b0\u7684T\u7ec6\u80de<\/strong><\/span><\/mark><\/strong><\/p>\n\n\n\n<p>\u5f53\u7814\u7a76\u4eba\u5458\u533a\u5206T\u7ec6\u80de\u65f6\uff0c\u4ed6\u4eec\u4f1a\u4f7f\u7528\u7ec6\u80de\u8868\u9762\u7684\u86cb\u767d\u8d28\u3002\u8f85\u52a9\u6027T\u7ec6\u80de\u53ef\u4ee5\u901a\u8fc7\u4e00\u79cd\u540d\u4e3aCD4\u7684\u86cb\u767d\u8d28\u6765\u8bc6\u522b\uff0c\u800c\u6740\u4f24\u6027T\u7ec6\u80de\u5219\u4ee5CD8\u4e3a\u7279\u5f81\u3002<\/p>\n\n\n\n<p><br>\u5728\u5742\u53e3\u5fd7\u6587\u4fdd\u62a4\u5c0f\u9f20\u514d\u53d7\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u653b\u51fb\u7684\u5b9e\u9a8c\u4e2d\uff0c\u4ed6\u4f7f\u7528\u4e86\u8868\u9762\u5e26\u6709CD4\u7684\u7ec6\u80de\u2014\u2014\u5373\u8f85\u52a9\u6027T\u7ec6\u80de\u3002\u901a\u5e38\u60c5\u51b5\u4e0b\uff0c\u8fd9\u4e9b\u7ec6\u80de\u4f1a\u5524\u9192\u514d\u75ab\u7cfb\u7edf\u5e76\u4f7f\u5176\u5f00\u59cb\u5de5\u4f5c\uff0c\u4f46\u5728\u5742\u53e3\u5fd7\u6587\u7684\u5b9e\u9a8c\u4e2d\uff0c\u514d\u75ab\u7cfb\u7edf\u5374\u53d7\u5230\u4e86\u6291\u5236\u3002\u4ed6\u7684\u7ed3\u8bba\u662f\uff0c\u5fc5\u5b9a\u5b58\u5728\u4e0d\u540c\u5f62\u5f0f\u7684\u3001\u643a\u5e26CD4\u7684T\u7ec6\u80de\u3002<\/p>\n\n\n\n<p><br>\u4e3a\u4e86\u68c0\u9a8c\u4ed6\u7684\u5047\u8bf4\uff0c\u5742\u53e3\u5fd7\u6587\u9700\u8981\u627e\u5230\u4e00\u79cd\u65b9\u6cd5\u6765\u533a\u5206\u5404\u79cd\u7c7b\u578b\u7684T\u7ec6\u80de\u3002\u8fd9\u82b1\u8d39\u4e86\u4ed6\u5341\u591a\u5e74\u7684\u65f6\u95f4\uff0c\u4f46\u57281995\u5e74\uff0c\u4ed6\u5411\u4e16\u754c\u5c55\u793a\u4e86\u4e00\u7c7b\u5168\u65b0\u7684T\u7ec6\u80de\u3002\u5728\u300a\u514d\u75ab\u5b66\u6742\u5fd7\u300b\uff08<em>The Journal of Immunology<\/em>\uff09\u4e0a\uff0c\u4ed6\u8bc1\u660e\u4e86\u8fd9\u4e9b\u80fd\u591f\u5e73\u606f\u514d\u75ab\u7cfb\u7edf\u7684T\u7ec6\u80de\uff0c\u5176\u7279\u5f81\u662f\u8868\u9762\u4e0d\u4ec5\u643a\u5e26CD4\uff0c\u8fd8\u5e26\u6709\u4e00\u79cd\u540d\u4e3aCD25\u7684\u86cb\u767d\u8d28\uff08\u56fe5\uff09\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"303\" src=\"https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_2-4.jpg\" alt=\"\" class=\"wp-image-3119\" srcset=\"https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_2-4.jpg 600w, https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_2-4-300x152.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure>\n\n\n\n<p><span style=\"color: rgb(153, 153, 153); font-size: 16px; letter-spacing: 1px;\">\u56fe5. \u5742\u53e3\u5fd7\u6587\u5b9a\u4e49\u4e86\u4e00\u7c7b\u65b0\u7684T\u7ec6\u80de \u00a9 \u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u59d4\u5458\u4f1a\u3002\u56fe\uff1aMattias Karl\u00e9n<\/span><\/p>\n\n\n\n<p><br>\u8fd9\u7c7b\u65b0\u53d1\u73b0\u7684T\u7ec6\u80de\u88ab\u547d\u540d\u4e3a\u8c03\u8282\u6027T\u7ec6\u80de\uff08regulatory T cells\uff09\u3002\u7136\u800c\uff0c\u8bb8\u591a\u7814\u7a76\u4eba\u5458\u5bf9\u8fd9\u79cd\u7ec6\u80de\u7684\u5b58\u5728\u4ecd\u6301\u6000\u7591\u6001\u5ea6\uff1b\u4ed6\u4eec\u9700\u8981\u66f4\u591a\u8bc1\u636e\u624d\u4f1a\u76f8\u4fe1\u5742\u53e3\u5fd7\u6587\u7684\u53d1\u73b0\u3002\u5173\u952e\u4fe1\u606f\u5c06\u6765\u81ea\u739b\u4e3d\u00b7\u5e03\u4f26\u79d1\u548c\u5f17\u96f7\u5fb7\u00b7\u62c9\u59c6\u65af\u5fb7\u5c14\u3002\u73b0\u5728\u662f2025\u5e74\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u6545\u4e8b\u7684\u7b2c\u4e8c\u5e55\u3002\u65b0\u7684\u6545\u4e8b\u5f00\u59cb\u4e8e20\u4e16\u7eaa40\u5e74\u4ee3\u7f8e\u56fd\u4e00\u4e2a\u5b9e\u9a8c\u5ba4\u91cc\u4e00\u53ea\u75c5\u5f31\u96c4\u6027\u5c0f\u9f20\u7684\u8bde\u751f\u3002<\/p>\n\n\n<p class=\"has-text-align-center has-medium-font-size\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0);\"><span style=\"font-size: 24px; text-decoration: overline; caret-color: rgb(8,124,186); color: rgb(8,124,186);\"><br><br><strong>\u4e00\u4e2a\u7a81\u53d8\u5f15\u53d1\u514d\u75ab\u7cfb\u7edf\u201c\u53db\u53d8\u201d<\/strong><\/span><\/mark><\/strong><\/p>\n\n\n<p>\u5728\u8fd9\u4e2a\u4f4d\u4e8e\u7530\u7eb3\u897f\u5dde\u6a61\u6811\u5cad\u7684\u5b9e\u9a8c\u5ba4\u91cc\uff0c\u7814\u7a76\u4eba\u5458\u6b63\u5728\u7814\u7a76\u8f90\u5c04\u7684\u540e\u679c\u3002\u4ed6\u4eec\u7684\u5de5\u4f5c\u662f\u66fc\u54c8\u987f\u8ba1\u5212\u548c\u539f\u5b50\u5f39\u7814\u53d1\u7684\u4e00\u90e8\u5206\u3002\u5728\u4eca\u5e74\u8bfa\u8d1d\u5c14\u5956\u4e2d\u626e\u6f14\u5173\u952e\u89d2\u8272\u7684\u5c0f\u9f20\u54c1\u7cfb\u662f\u4e00\u6b21\u6f14\u5316\u4e0a\u7684\u5076\u7136\u2014\u2014\u4e00\u4e9b\u96c4\u6027\u5c0f\u9f20\u610f\u5916\u5730\u51fa\u751f\u65f6\u76ae\u80a4\u9cde\u5c51\u5c31\u5df2\u7ecf\u5265\u843d\uff0c\u813e\u810f\u548c\u6dcb\u5df4\u817a\u6781\u5ea6\u80bf\u5927\uff0c\u5e76\u4e14\u53ea\u80fd\u5b58\u6d3b\u51e0\u5468\u3002<\/p>\n\n\n\n<p><br>\u8fd9\u4e2a\u540d\u53eb scurfy \u7684\u5c0f\u9f20\u54c1\u7cfb\u5f15\u8d77\u4e86\u7814\u7a76\u4eba\u5458\u7684\u6ce8\u610f\u3002\u5f53\u65f6\u5206\u5b50\u9057\u4f20\u5b66\u5c1a\u5904\u4e8e\u8d77\u6b65\u9636\u6bb5\uff0c\u4f46\u4ed6\u4eec\u610f\u8bc6\u5230\u5bfc\u81f4\u8fd9\u79cd\u75be\u75c5\u7684\u7a81\u53d8\u5fc5\u5b9a\u4f4d\u4e8e\u5c0f\u9f20\u7684X\u67d3\u8272\u4f53\u4e0a\u3002\u6240\u6709\u96c4\u6027\u5c0f\u9f20\u4e2d\u6709\u4e00\u534a\u4f1a\u60a3\u75c5\uff0c\u4f46\u96cc\u6027\u5c0f\u9f20\u53ef\u4ee5\u5728\u643a\u5e26\u6b64\u7a81\u53d8\u65f6\u5b58\u6d3b\uff0c\u56e0\u4e3a\u5b83\u4eec\u6709\u4e24\u6761X\u67d3\u8272\u4f53\uff0c\u5176\u4e2d\u4e00\u6761\u5e26\u6709\u5065\u5eb7\u7684DNA\u3002\u56e0\u6b64\uff0c\u96cc\u6027\u5c0f\u9f20\u4f1a\u5c06 scurfy \u7a81\u53d8\u4f20\u9012\u7ed9\u540e\u4ee3\u3002<\/p>\n\n\n\n<p><br>\u5230\u4e8620\u4e16\u7eaa90\u5e74\u4ee3\uff0c\u5404\u79cd\u5206\u5b50\u5de5\u5177\u5df2\u53d8\u5f97\u76f8\u5f53\u7cbe\u826f\uff0c\u7814\u7a76\u4eba\u5458\u5f00\u59cb\u7814\u7a76\u96c4\u6027 scurfy \u5c0f\u9f20\u75c5\u5f97\u5982\u6b64\u4e25\u91cd\u7684\u539f\u56e0\u3002\u7ed3\u679c\u53d1\u73b0\uff0c\u5b83\u4eec\u7684\u5668\u5b98\u6b63\u53d7\u5230 T \u7ec6\u80de\u7684\u653b\u51fb\uff0c\u8fd9\u4e9b T \u7ec6\u80de\u7834\u574f\u4e86\u7ec4\u7ec7\u3002\u51fa\u4e8e\u67d0\u79cd\u539f\u56e0\uff0cscurfy \u7a81\u53d8\u4f3c\u4e4e\u5728\u514d\u75ab\u7cfb\u7edf\u4e2d\u5f15\u53d1\u4e86\u4e00\u573a\u201c\u53db\u4e71\u201d\u3002<\/p>\n\n\n<p class=\"has-text-align-center has-medium-font-size\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0);\"><span style=\"font-size: 24px; text-decoration: overline; caret-color: rgb(8,124,186); color: rgb(8,124,186);\"><br><br><strong>\u5e03\u4f26\u79d1\u548c\u62c9\u59c6\u65af\u5fb7\u5c14\u4e3a\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u5bfb\u627e\u89e3\u91ca<\/strong><\/span><\/mark><\/strong><\/p>\n\n\n<p><br>\u5728\u5bf9 scurfy \u7a81\u53d8\u4ea7\u751f\u5174\u8da3\u7684\u7814\u7a76\u4eba\u5458\u4e2d\uff0c\u6709\u4e24\u4f4d\u5c31\u662f\u739b\u4e3d\u00b7\u5e03\u4f26\u79d1\u548c\u5f17\u96f7\u5fb7\u00b7\u62c9\u59c6\u65af\u5fb7\u5c14\u3002\u4ed6\u4eec\u5728\u7f8e\u56fd\u534e\u76db\u987f\u5dde\u535a\u585e\u5c14\u7684\u4e00\u5bb6\u540d\u4e3a Celltech Chiroscience \u7684\u751f\u7269\u6280\u672f\u516c\u53f8\u5de5\u4f5c\u3002\u8be5\u516c\u53f8\u5f00\u53d1\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u836f\u7269\uff0c\u5e03\u4f26\u79d1\u548c\u62c9\u59c6\u65af\u5fb7\u5c14\u610f\u8bc6\u5230scurfy\u5c0f\u9f20\u53ef\u4ee5\u4e3a\u4ed6\u4eec\u7684\u5de5\u4f5c\u63d0\u4f9b\u91cd\u8981\u7ebf\u7d22\u3002\u5982\u679c\u4ed6\u4eec\u80fd\u591f\u7406\u89e3\u5c0f\u9f20\u75be\u75c5\u80cc\u540e\u7684\u5206\u5b50\u673a\u5236\uff0c\u4ed6\u4eec\u5c31\u80fd\u83b7\u5f97\u5173\u4e8e\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u8d77\u6e90\u7684\u51b3\u5b9a\u6027\u89c1\u89e3\u3002\u4e8e\u662f\uff0c\u4ed6\u4eec\u505a\u51fa\u4e86\u4e00\u4e2a\u5173\u952e\u51b3\u5b9a\uff1a\u5bfb\u627escurfy\u5c0f\u9f20\u7684\u7a81\u53d8\u57fa\u56e0\u3002<\/p>\n\n\n\n<p><br>\u5982\u4eca\uff0c\u5728\u51e0\u5929\u5185\u7ed8\u5236\u51fa\u5c0f\u9f20\u7684\u6574\u4e2a\u57fa\u56e0\u7ec4\u5e76\u627e\u5230\u4e00\u4e2a\u7a81\u53d8\u57fa\u56e0\u5e76\u4e0d\u56f0\u96be\u3002\u4f46\u572820\u4e16\u7eaa90\u5e74\u4ee3\uff0c\u8fd9\u5c31\u50cf\u5927\u6d77\u635e\u9488\u3002\u6784\u6210\u5c0f\u9f20 X \u67d3\u8272\u4f53\u7684DNA\u94fe\u7531\u5927\u7ea6 1.7 \u4ebf\u4e2a\u78b1\u57fa\u5bf9\u7ec4\u6210\u3002\u5728\u8fd9\u5e9e\u5927\u7684DNA \u4e2d\u627e\u5230\u4e00\u4e2a\u7a81\u53d8\u5f53\u7136\u53ef\u80fd\uff0c\u4f46\u8fd9\u9700\u8981\u65f6\u95f4\u3001\u8010\u5fc3\u4ee5\u53ca\u5bf9\u90a3\u4e2a\u65f6\u4ee3\u5206\u5b50\u751f\u7269\u5b66\u5de5\u5177\u7684\u521b\u9020\u6027\u8fd0\u7528\u3002<\/p>\n\n\n<p class=\"has-text-align-center has-medium-font-size\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0);\"><span style=\"font-size: 24px; text-decoration: overline; caret-color: rgb(8,124,186); color: rgb(8,124,186);\"><br><br><strong>\u5e03\u4f26\u79d1\u548c\u62c9\u59c6\u65af\u5fb7\u5c14\u5728DNA\u7684\u8349\u5806\u4e2d\u627e\u5230\u4e86\u90a3\u6839\u9488<\/strong><\/span><\/mark><\/strong><\/p>\n\n\n<p><br>\u57fa\u56e0\u5b9a\u4f4d\u663e\u793a\uff0cscurfy \u7a81\u53d8\u5fc5\u5b9a\u4f4d\u4e8e X \u67d3\u8272\u4f53\u7684\u4e2d\u90e8\u67d0\u5904\u3002\u5e03\u4f26\u79d1\u548c\u62c9\u59c6\u65af\u5fb7\u5c14\u6210\u529f\u5730\u5c06\u53ef\u80fd\u533a\u57df\u7f29\u5c0f\u5230\u5927\u7ea650\u4e07\u4e2a\u6838\u82f7\u9178\u3002\u7136\u540e\uff0c\u4ed6\u4eec\u5f00\u59cb\u4e86\u4e00\u9879\u8270\u96be\u7684\u5de5\u4f5c\u2014\u2014\u8be6\u7ec6\u7ed8\u5236\u8fd9\u4e2a\u533a\u57df\u7684 X \u67d3\u8272\u4f53\u3002<\/p>\n\n\n\n<p><br>\u8fd9\u82b1\u8d39\u4e86\u5f88\u957f\u65f6\u95f4\u3002\u5f53\u5e03\u4f26\u79d1\u548c\u62c9\u59c6\u65af\u5fb7\u5c14\u5b8c\u6210\u8fd9\u9879\u5de5\u4f5c\u65f6\uff0c\u4ed6\u4eec\u627e\u5230\u4e86\u8be5\u533a\u57df\u768420\u4e2a\u6f5c\u5728\u57fa\u56e0\u3002\u4ed6\u4eec\u7684\u4e0b\u4e00\u4e2a\u6311\u6218\u662f\u6bd4\u8f83\u5065\u5eb7\u5c0f\u9f20\u548cscurfy\u5c0f\u9f20\u7684\u8fd9\u4e9b\u57fa\u56e0\u3002\u4ed6\u4eec\u9010\u4e00\u68c0\u67e5\u8fd9\u4e9b\u57fa\u56e0\uff0c\u76f4\u5230\u68c0\u67e5\u5230\u7b2c20\u4e2a\u4e5f\u662f\u6700\u540e\u4e00\u4e2a\u57fa\u56e0\u65f6\uff0c\u4ed6\u4eec\u624d\u6709\u6240\u6536\u83b7\u3002\u7ecf\u8fc7\u591a\u5e74\u7684\u4e13\u6ce8\u5de5\u4f5c\uff0c\u4ed6\u4eec\u7ec8\u4e8e\u627e\u5230\u4e86scurfy\u7a81\u53d8\uff08\u56fe6\uff09\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"335\" src=\"https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_11.jpg\" alt=\"\" class=\"wp-image-3123\" srcset=\"https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_11.jpg 600w, https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_11-300x168.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure>\n\n\n\n<p><span style=\"color: rgb(153, 153, 153); font-size: 16px; letter-spacing: 1px;\">\u56fe6. \u5e03\u4f26\u79d1\u548c\u62c9\u59c6\u65af\u5fb7\u5c14\u627e\u5230scurfy\u7a81\u53d8 \u00a9 \u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u59d4\u5458\u4f1a\u3002\u56fe\uff1aMattias Karl\u00e9n<\/span><\/p>\n\n\n\n<p><br>\u8fd9\u4e2a\u6709\u7f3a\u9677\u7684\u57fa\u56e0\u4ee5\u524d\u662f\u672a\u77e5\u7684\uff0c\u4f46\u4e0e\u4e00\u7ec4\u540d\u53eb\u201c\u53c9\u5934\u6846\u201d \uff08forkhead box\uff09\u6216\u00a0<em>FOX\u00a0<\/em>\u7684\u57fa\u56e0\u6709\u8bb8\u591a\u76f8\u4f3c\u4e4b\u5904\u3002\u8fd9\u4e9b\u57fa\u56e0\u4f1a\u8c03\u8282\u5176\u4ed6\u57fa\u56e0\u7684\u6d3b\u6027\uff0c\u4ece\u800c\u5f71\u54cd\u7ec6\u80de\u53d1\u80b2\u3002\u739b\u4e3d\u00b7\u5e03\u4f26\u79d1\u548c\u5f17\u96f7\u5fb7\u00b7\u62c9\u59c6\u65af\u5fb7\u5c14\u5c06\u8fd9\u4e2a\u65b0\u57fa\u56e0\u547d\u540d\u4e3a<em>\u00a0Foxp3<\/em>\u3002<\/p>\n\n\n<p class=\"has-text-align-center has-medium-font-size\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0);\"><span style=\"font-size: 24px; text-decoration: overline; caret-color: rgb(8,124,186); color: rgb(8,124,186);\"><br><br><strong>\u4ed6\u4eec\u7684\u53d1\u73b0\u63ed\u793a\u4e86\u4e00\u79cd\u4eba\u7c7b\u4e25\u91cd\u75be\u75c5\u7684\u75c5\u56e0<\/strong><\/span><\/mark><\/strong><\/p>\n\n\n<p><br>\u5728\u7814\u7a76\u8fc7\u7a0b\u4e2d\uff0c\u5e03\u4f26\u79d1\u548c\u62c9\u59c6\u65af\u5fb7\u5c14\u5f00\u59cb\u6000\u7591\u4e00\u79cd\u7f55\u89c1\u7684\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u2014\u2014\u540c\u6837\u4e0eX\u67d3\u8272\u4f53\u76f8\u5173\u7684IPEX\u7efc\u5408\u5f81\uff0c\u53ef\u80fd\u662fscurfy\u5c0f\u9f20\u75be\u75c5\u7684\u4eba\u7c7b\u5bf9\u5e94\u7248\u672c\u3002\u5728\u641c\u7d22\u4e00\u4e2a\u79d1\u5b66\u5bb6\u5b58\u50a8\u65b0\u53d1\u73b0\u57fa\u56e0\u4fe1\u606f\u7684\u6570\u636e\u5e93\u65f6\uff0c\u4ed6\u4eec\u627e\u5230\u4e86\u4eba\u7c7b\u7684\u00a0<em>Foxp3\u00a0<\/em>\u5bf9\u5e94\u57fa\u56e0\u3002\u5728\u4e16\u754c\u5404\u5730\u513f\u79d1\u533b\u751f\u7684\u5e2e\u52a9\u4e0b\uff0c\u4ed6\u4eec\u6536\u96c6\u4e86\u60a3\u6709IPEX\u7efc\u5408\u5f81\u7537\u5b69\u7684\u6837\u672c\u3002\u5f53\u4ed6\u4eec\u5bf9\u6837\u672c\u8fdb\u884c\u57fa\u56e0\u6d4b\u5e8f\u65f6\uff0c\u786e\u5b9e\u5728\u00a0<em>FOXP3<\/em>\u00a0\u57fa\u56e0\u4e2d\u5b58\u5728\u6709\u5bb3\u7a81\u53d8\u3002<\/p>\n\n\n\n<p><br>2001\u5e74\uff0c\u5728\u300a\u81ea\u7136-\u9057\u4f20\u5b66\u300b\u6742\u5fd7\u4e0a\uff0c\u739b\u4e3d\u00b7\u5e03\u4f26\u79d1\u548c\u5f17\u96f7\u5fb7\u00b7\u62c9\u59c6\u65af\u5fb7\u5c14\u53d1\u8868\u7814\u7a76\uff0c\u63ed\u793a\u4e86<em>\u00a0FOXP3<\/em>\u00a0\u57fa\u56e0\u7684\u7a81\u53d8\u65e2\u5bfc\u81f4\u4e86\u540d\u53eb IPEX\u7684\u4eba\u7c7b\u75be\u75c5\uff0c\u4e5f\u5bfc\u81f4\u4e86scurfy\u5c0f\u9f20\u7684\u75c5\u75c7\u3002\u8fd9\u4e9b\u5173\u952e\u53d1\u73b0\u5f15\u53d1\u4e86\u591a\u4e2a\u5b9e\u9a8c\u5ba4\u7684\u72c2\u70ed\u7814\u7a76\u3002\u5f53\u7814\u7a76\u4eba\u5458\u5c06\u8fd9\u4e9b\u7ebf\u7d22\u62fc\u51d1\u5728\u4e00\u8d77\u65f6\uff0c\u4ed6\u4eec\u610f\u8bc6\u5230\u00a0<em>FOXP3<\/em>\u00a0\u57fa\u56e0\u53ef\u80fd\u5bf9\u5742\u53e3\u5fd7\u6587\u53d1\u73b0\u7684\u8c03\u8282\u6027T\u7ec6\u80de\u81f3\u5173\u91cd\u8981\u3002<\/p>\n\n\n<p class=\"has-text-align-center has-medium-font-size\"><strong><mark style=\"background-color:rgba(0, 0, 0, 0);\"><span style=\"font-size: 24px; text-decoration: overline; caret-color: rgb(8,124,186); color: rgb(8,124,186);\"><br><br><strong>\u8c03\u8282\u6027T\u7ec6\u80de\u2014\u2014\u8eab\u4f53\u7684\u201c\u5b89\u5168\u536b\u58eb\u201d<\/strong><\/span><\/mark><\/strong><\/p>\n\n\n<p><br>\u4e24\u5e74\u540e\uff0c\u5742\u53e3\u5fd7\u6587\u2014\u2014\u4ee5\u53ca\u5f88\u5feb\u52a0\u5165\u7684\u5176\u4ed6\u7814\u7a76\u4eba\u5458\u2014\u2014\u4ee4\u4eba\u4fe1\u670d\u5730\u8bc1\u660e\u4e86\u00a0<em>FOXP3\u00a0<\/em>\u57fa\u56e0\u63a7\u5236\u7740\u8c03\u8282\u6027T\u7ec6\u80de\u7684\u53d1\u80b2\u3002\u8fd9\u4e9b\u7ec6\u80de\u963b\u6b62\u5176\u4ed6T\u7ec6\u80de\u9519\u8bef\u5730\u653b\u51fb\u8eab\u4f53\u81ea\u8eab\u7ec4\u7ec7\uff08\u56fe7\uff09\uff0c\u8fd9\u5bf9\u4e8e\u4e00\u4e2a\u540d\u53eb\u201c\u5916\u5468\u514d\u75ab\u8010\u53d7\u201d\uff08peripheral immune tolerance\uff09\u7684\u8fc7\u7a0b\u81f3\u5173\u91cd\u8981\u3002\u8c03\u8282\u6027T\u7ec6\u80de\u8fd8\u786e\u4fdd\u514d\u75ab\u7cfb\u7edf\u5728\u6e05\u9664\u5165\u4fb5\u8005\u540e\u5e73\u606f\u4e0b\u6765\uff0c\u4ece\u800c\u4e0d\u4f1a\u6301\u7eed\u9ad8\u901f\u8fd0\u8f6c\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"289\" src=\"https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_8-2.jpg\" alt=\"\" class=\"wp-image-3121\" srcset=\"https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_8-2.jpg 600w, https:\/\/www.huanqiukexue.com\/wp-content\/uploads\/2025\/10\/wechat_image_8-2-300x145.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure>\n\n\n\n<p><span style=\"color: rgb(153, 153, 153); font-size: 16px; letter-spacing: 1px;\">\u56fe7. \u8c03\u8282\u6027T\u7ec6\u80de\u5982\u4f55\u4fdd\u62a4\u6211\u4eec \u00a9 \u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u59d4\u5458\u4f1a\u3002\u56fe\uff1aMattias Karl\u00e9n<\/span><\/p>\n\n\n\n<p><br>\u7814\u7a76\u4eba\u5458\u901a\u8fc7\u53d1\u73b0\u8c03\u8282\u6027T\u7ec6\u80de\u53ca\u5176\u5728\u5916\u5468\u514d\u75ab\u8010\u53d7\u4e2d\u7684\u91cd\u8981\u6027\u6240\u83b7\u5f97\u7684\u57fa\u7840\u77e5\u8bc6\uff0c\u63a8\u52a8\u4e86\u6f5c\u5728\u65b0\u533b\u7597\u65b9\u6cd5\u7684\u53d1\u5c55\u3002\u5bf9\u80bf\u7624\u7684\u5206\u6790\u8868\u660e\uff0c\u80bf\u7624\u80fd\u591f\u5438\u5f15\u5927\u91cf\u8c03\u8282\u6027T\u7ec6\u80de\u6765\u4fdd\u62a4\u81ea\u5df1\u514d\u53d7\u514d\u75ab\u7cfb\u7edf\u7684\u653b\u51fb\u3002\u56e0\u6b64\uff0c\u7814\u7a76\u4eba\u5458\u6b63\u8bd5\u56fe\u627e\u5230\u65b9\u6cd5\u62c6\u9664\u8fd9\u5835\u7531\u8c03\u8282\u6027T\u7ec6\u80de\u6784\u6210\u7684\u201c\u5899\u201d\uff0c\u4ee5\u4fbf\u514d\u75ab\u7cfb\u7edf\u80fd\u591f\u63a5\u89e6\u5230\u80bf\u7624\u3002<\/p>\n\n\n\n<p><br>\u5bf9\u4e8e\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u6cbb\u7597\uff0c\u7814\u7a76\u4eba\u5458\u5219\u53cd\u8fc7\u6765\u589e\u52a0\u8c03\u8282\u6027T\u7ec6\u80de\u7684\u5f62\u6210\u3002\u5728\u521d\u6b65\u7814\u7a76\u4e2d\uff0c\u4ed6\u4eec\u7ed9\u60a3\u8005\u4f7f\u7528\u767d\u7ec6\u80de\u4ecb\u7d20-2\uff0c\u8fd9\u662f\u4e00\u79cd\u80fd\u4fc3\u8fdb\u8c03\u8282\u6027T\u7ec6\u80de\u589e\u6b96\u7684\u7269\u8d28\u3002\u7814\u7a76\u4eba\u5458\u8fd8\u5728\u7814\u7a76\u767d\u7ec6\u80de\u4ecb\u7d20-2\u662f\u5426\u53ef\u7528\u4e8e\u9884\u9632\u5668\u5b98\u79fb\u690d\u540e\u7684\u6392\u65a5\u53cd\u5e94\u3002<\/p>\n\n\n\n<p><br>\u7814\u7a76\u4eba\u5458\u6b63\u5728\u6d4b\u8bd5\u53e6\u4e00\u79cd\u51cf\u7f13\u8fc7\u5ea6\u6d3b\u8dc3\u514d\u75ab\u7cfb\u7edf\u7684\u7b56\u7565\uff1a\u4ece\u60a3\u8005\u4f53\u5185\u5206\u79bb\u51fa\u8c03\u8282\u6027T\u7ec6\u80de\uff0c\u5e76\u5728\u5b9e\u9a8c\u5ba4\u4e2d\u8fdb\u884c\u6269\u589e\u3002\u7136\u540e\u5c06\u8fd9\u4e9b\u7ec6\u80de\u56de\u8f93\u5230\u60a3\u8005\u4f53\u5185\uff0c\u4ece\u800c\u4f7f\u60a3\u8005\u4f53\u5185\u62e5\u6709\u66f4\u591a\u7684\u8c03\u8282\u6027T\u7ec6\u80de\u3002\u5728\u67d0\u4e9b\u60c5\u51b5\u4e0b\uff0c\u7814\u7a76\u4eba\u5458\u8fd8\u4f1a\u5bf9T\u7ec6\u80de\u8fdb\u884c\u6539\u9020\uff0c\u5728\u5b83\u4eec\u8868\u9762\u52a0\u4e0a\u50cf\u5730\u5740\u6807\u7b7e\u4e00\u6837\u7684\u6297\u4f53\u3002\u8fd9\u4f7f\u5f97\u7814\u7a76\u4eba\u5458\u80fd\u591f\u5c06\u8fd9\u4e9b\u7ec6\u80de\u201c\u5b89\u5168\u536b\u58eb\u201d\u6d3e\u5f80\u79fb\u690d\u7684\u809d\u810f\u6216\u80be\u810f\u7b49\uff0c\u4fdd\u62a4\u5668\u5b98\u514d\u53d7\u514d\u75ab\u7cfb\u7edf\u7684\u653b\u51fb\u3002<\/p>\n\n\n\n<p><br>\u5173\u4e8e\u7814\u7a76\u4eba\u5458\u5982\u4f55\u6d4b\u8bd5\u5229\u7528\u8c03\u8282\u6027T\u7ec6\u80de\u6765\u5bf9\u6297\u75be\u75c5\u7684\u4f8b\u5b50\u8fd8\u6709\u5f88\u591a\u3002\u901a\u8fc7\u4ed6\u4eec\u7684\u9769\u547d\u6027\u53d1\u73b0\uff0c\u739b\u4e3d\u00b7\u5e03\u4f26\u79d1\u3001\u5f17\u96f7\u5fb7\u00b7\u62c9\u59c6\u65af\u5fb7\u5c14\u548c\u5742\u53e3\u5fd7\u6587\u4e3a\u6211\u4eec\u63d0\u4f9b\u4e86\u5173\u4e8e\u514d\u75ab\u7cfb\u7edf\u5982\u4f55\u88ab\u8c03\u63a7\u548c\u6291\u5236\u7684\u57fa\u7840\u77e5\u8bc6\u3002\u4ed6\u4eec\u56e0\u6b64\u4e3a\u5168\u4eba\u7c7b\u5e26\u6765\u4e86\u6700\u5927\u7684\u798f\u7949\u3002<\/p>\n\n\n\n<p><br>\u8bfa\u8d1d\u5c14\u5956\u5b98\u65b9\u7f51\u7ad9\uff1a<a href=\"https:\/\/www.nobelprize.org\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.nobelprize.org\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4e24\u4f4d\u7f8e\u56fd\u5b66\u8005\u3001\u4e00\u4f4d\u65e5\u672c\u5b66\u8005\u83b7\u5956\u3002<\/p>\n","protected":false},"author":3,"featured_media":3124,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8,5],"tags":[397],"class_list":["post-3118","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lead","category-health","tag-397"],"_links":{"self":[{"href":"https:\/\/www.huanqiukexue.com\/index.php?rest_route=\/wp\/v2\/posts\/3118","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.huanqiukexue.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.huanqiukexue.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.huanqiukexue.com\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.huanqiukexue.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3118"}],"version-history":[{"count":5,"href":"https:\/\/www.huanqiukexue.com\/index.php?rest_route=\/wp\/v2\/posts\/3118\/revisions"}],"predecessor-version":[{"id":3157,"href":"https:\/\/www.huanqiukexue.com\/index.php?rest_route=\/wp\/v2\/posts\/3118\/revisions\/3157"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.huanqiukexue.com\/index.php?rest_route=\/wp\/v2\/media\/3124"}],"wp:attachment":[{"href":"https:\/\/www.huanqiukexue.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3118"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.huanqiukexue.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3118"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.huanqiukexue.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3118"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}